|
1 / 1
|
DeCS
|
|
 |
|
Descriptor English:
|
|
Polyendocrinopathies, Autoimmune
|
|
Descriptor Spanish:
|
|
Poliendocrinopatías Autoinmunes
|
|
Descriptor Portuguese:
|
|
Poliendocrinopatias Autoimunes
|
|
Synonyms English:
|
|
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
Autoimmune Syndrome Type I, Polyglandular
Autoimmune Syndrome Type II, Polyglandular
Polyglandular Type I Autoimmune Syndrome
Polyglandular Type II Autoimmune Syndrome
Schmidt's Syndrome
|
|
Tree Number:
|
|
C19.787
C20.111.750
|
|
Definition English:
|
|
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present. |
|
Indexing Annotation English:
|
|
do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed
|
|
History Note English:
|
|
1992
|
|
Allowable Qualifiers English:
|
|
|
|
Record Number:
|
|
29879
|
|
Unique Identifier:
|
|
D016884
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|